CHOLINE ALFOSCERATE - AOR

 

Available at Vitamin Wagon

CHOLINE ALFOSCERATE
60 Vegi-Caps
Choline Alfoscerate
is L-a-glyceryl phosphorylcholine (GPC),a key brain cell membrane phospholipid and cholinergic precursor. It is a source of choline for the synthesis of the neurotransmitter acetylcholine, with a greater ability to penetrate the blood-brain barrier than conventional choline sources. More importantly, Choline alfoscerate has been experimentally demonstrated to reduce or reverse age-related structural changes in the frontal cortex and hippocampus and induced functional deficiencies of the cholinergic system. Research supports choline alfoscerates ability to support healthy brain function and the release of somatotrophin (hGH).
The aging brain's cholinergic function is impaired at several points, all of which affect mental performance:
• The ability of the brain to take in necessary raw materials.
• The loss of balance in key cholinergic enzymes.
• The loss of choinergic neurons.

Choline alfoscerate (al-FOSS-er-ate), or alpha-glycerylphosphorylcholine (GPC), is a phospholipid - a complex fatty substance containing phosphorus, like phosphatidylserine and phosphatidylcholine - and is an important building block in the construction of nerve cell membranes. After completing an analysis of thirteen published clinical trials, involving over 4000 patients, a group of Italian scientists concluded that "The stated therapeutic usefulness of Choline Alfoscerate in the relief of cognitive symptoms, such as memory and attention impairment, differentiates [it] from cholinergic precursors used in former clinical trials", such as choline, lecithin, or phosphatidylcholine. The reason, as evidence now suggests, is that the effects of this versatile nutrient extend well beyond its role as a mere choline source: choline alfoscerate supports the restoration of a whole spectrum of youthful cholinergic functions.

Weak Link 1: Decreased Choline UptakeCholine alfoscerate is a rapidly absorbed source of choline, which easily enters the brain. GPC raises free plasma choline more rapidly than other uncharged choline precursors. Because it is a phospholipid - the same sort of material of which the brain and Blood-Brain Barrier (BBB) are made - Choline Alfoscerate does not carry the electrical charge of regular choline, and so freely crosses the blood-brain barrier. The choline from Choline Alfoscerate is incorporated into brain phospholipids within 24 hours of absorption.

Weak Link 2: Enzyme ImbalancesThe brain makes acetylcholine using an enzyme known as choline acetyltransferase. As we get older, ChAT activity goes down, while the activity of enzymes that break down chat goes up. As a result, aging brains make less acetylcholine from the choline available to them, while they tear acetylcholine down more quickly. Animal studies suggest that Choline Alfoscerate may also improve the levels of ChAT.

Weak Link 3: Brain DrainThis is perhaps the most serious issue facing the aging brain: the cholinergic neurons of the brain simply wither away with age. The number of neurons declines, and those neurons that remain literally shrink, becoming less well-connected to the rest of the brain. This decay is made all the worse by the fact that the ability of the surviving cholinergic neurons to release and respond to ACh is also impaired with age!

There are two main reasons for this loss of function. First, the composition of the nerve cell membrane is altered with age, becoming less flexible and responsive. This makes it harder for the neuron which is sending the signal to release the ACh messenger, and harder for the receiving neuron to pick it up. Choline alfoscerate restores membrane and fluidity responsiveness, both because having more Choline Alfoscerate in the membrane directly makes the membrane more fluid, and perhaps because Choline Alfoscerate inhibits an enzyme (lysophospholipase) that breaks down some brain phospholipids.

Second, some of the receptors to which ACh is designed to bind - the "mailbox" to which they are addressed - also decline with age. This is especially true of the muscarinic-type-1 (M1) receptors - the ones involved in higher mental function. While most other cholinergic receptors remain plentiful throughout life. Fortunately, Choline Alfoscerate selectively restores the number of memory-specific cholinergic receptors.

Even more incredibly, animal studies show that Choline Alfoscerate actually increases the number of cholinergic neurons as well. In addition, Choline Alfoscerate may reverse the atrophy of existing cholinergic neurons, since studies show that Choline Alfoscerate increases the number of receptors for nerve growth factor (NGF). Supplying NGF to old monkeys clearly reverses cholinergic neuron atrophy, restoring the number and size of these neurons to more youthful levels.

Controlled Trials: It WorksIn one controlled trial in victims of vascular dementia, greater improvements on several measures of cognitive function were seen amongst those patients treated with Choline Alfoscerate than in those given another choline precursor. The differences were statistically significant, and both patients and physicians rated the results with GPC more satisfactory.

Another controlled trial in Alzheimer's disease compared Choline Alfoscerate to acetyl-L-carnitine (ALCAR), a nutrient already proven to slow the progression of AD in younger patients. Most behavioral and mental function test results showed improvement in the Choline Alfoscerate group - and the improvements were greater than those seen in the ALCAR group.

Yet another trial monitored the progress of 2044 patients who were being treated with Choline Alfoscerate after recent strokes or transient ischemic attacks (TIAs - sometimes called "mini-strokes"). Statistically significant improvements were seen on several scales of cognitive performance, such that the Mini Mental State (MMS) score was found to be within the normal range, Chrichton Rating Scale (CRS) decreased by a significant 4.3 points, and the Global Deterioration Scale scores indicated "no cognitive decline" or "forgetfulness" rather than clinical mental impairment.

There is also a hint that Choline Alfoscerate may prove of use in Parkinson's disease (PD). PD is characterized by reductions in the production of the neurotransmitter dopamine in an area of the brain called the substantia nigra. This leads to a loss of motor control, typically manifesting in facial ticks or tremors, dry mouth, and a "masklike" facial expression. In laboratory animals, measures of dopaminergic activity were enhanced by GPC treatment.
60 Vegi-Caps      100% Vegetarian
______________________________________________
SUPPLEMENT FACTS:
Serving Size: 1 Capsule                                        %DRI______________________________________________
L-a-glyceryl phosphorylcholine ............. 250 mg            *
______________________________________________

*Dietary Reference Intake not established.
Other ingredients: microcrystalline cellulose. Capsule: hypromellose, sorbitol, silicon dioxide, water.

AOR guarantees that no ingredients not listed on the label have been added to the product. Contains no wheat, gluten, corn, nuts, dairy, eggs, fish or shellfish.

Suggested Use
Take two to four capsules daily, or as directed by a qualified health care practitioner.

Main Applications
As reported by literature:
Support in Alzheimer's disease
Cognitive support
Infant brain development

Source
Purified from lecithin.

Pregnancy / Nursing
Safe at 1-2 capsules per day.

Cautions
None known.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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Ortho•Mind - AOR

 

Available at Vitamin Wagon

Ortho•Mind
180 Vegi-Caps 100% VegetarianReformulated to provide the best possible product to our customers for the support of optimal cognitive health! 

Ortho-Mind is a superior multi-nutrient formula including ingredients supported by the latest research. These ingredients include nutrients like citicoline and Acetyl-L-Carnitine as well as natural botanical extracts like gingko biloba, panax ginseng and bacopa.

Changes to the formula include the removal of vinpocetine and Huperzine-A and the addition of 100mg of Panax ginseng. Pyroglutamic acid has been replaced with the more effective L-Arginine-L-Pyroglutamic acid.  All other ingredients, including Acetyl-L-Carnitine, Bacopa, Ginkgo, Citicoline and Vitamin B5 remain unchanged.

click here for supplemental facts

Suggested Use
Take up to 6 capsules daily, or as directed by a qualified health care practitioner.

AOR guarantees that no ingredients not listed on the label have been added to the product.
Contains no wheat, gluten, corn, nuts, dairy, soy, eggs, fish or shellfish or any animal byproduct. 

Caution: 
Do not use if you are pregnant or nursing, have had a heart attack/myocardial infarction, or are taking medications or health products that affect blood coagulation (e.g. blood thinners, clotting factor replacements, acetylsalicylic acid, ibuprofen, fish oils, vitamin E) as this may increase the risk of spontaneous bleeding. Consult a health care practitioner prior to use if you have diabetes, cardiovascular disease and are attempting to increase physical activity, renal/kidney disease, are following a low protein diet or are taking digoxin, antidepressant medications, or medications for cardiovascular diseases, diabetes, erectile dysfunction, high blood pressure or seizures. Some people may experience gastrointestinal discomfort (such as diarrhea), insomnia, anxiety, or headaches, in which case, discontinue use.  

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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Bilberry - FoodScience of Vermont

 

Available at Vitamin Wagon

Bilberry (90 Capsules)  Rich in anthocyanosides, this northern shrub with berries similar to blueberries has traditionally been used to reduce eyestrain and support proper visual functions. It's also helpful in dealing with circulatory insufficiencies and vascular strength by helping to synthesize compounds that maintain artery walls.*

Each capsule contains 80 mg Bilberry (Vaccinium myrtillus L.) standardized to yield 20 mg anthocyanosides.

Other ingredients: rice powder, gelatin, water, magnesium stearate.

As a dietary supplement, take 1-3 capsules daily with meals.

* This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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NT Factor EnergyLipids Powder - Allergy Research Group

 

Available at Vitamin Wagon

 
NT Factor EnergyLipids Powder 150 grams

Patent-pending phosphoglycolipids from soy, in proprietary and scientifically selected ratios of phosphatidylcholine,
glycolipids, and other phosphatidyl nutrients, researched and blended to optimize cellular uptake and membrane utilization.*
Suggested Use: As a dietary supplement, ¼ teaspoon two times daily, or as directed by a healthcare practitioner.
A larger dose of ½ teaspoon two times daily may be taken during an initial one to two month loading period.
May be mixed with water, juice, or food.

Serving Size ¼ Teaspoon (1.25 g) Servings per container 120 Amount per serving:   Calories 8 Calories from Fat 5 NT Factor Proprietary Lipid Blend (soy lecithin extract) 1087 mg Phosphatidic acid (PA)   Phosphatidyl-choline (PC)   Phosphatidyl-ethanolamine (PE)   Phosphatidyl-glycerol(PG)   Phosphatidyl-inositol (PI)   Phosphatidyl-serine (PS)   Digalactosyldiacylglyceride (DGDG)   Monoglactosyldiacylglyceride (MGDG)

Other ingredients: Fructooligosaccharides (FOS), pantethine, sodium borate, rosemary extract.
Store tightly sealed at room temperature, away from direct sunlight.

Variations in product color may occur. Keep in a cool, dry place, tightly capped.

*This statement has not been evaluated by the U.S. Food and Drug administration. The product is not intended to diagnose, treat, cure, or prevent any disease.

~Vitamin Wagon carries quality products at competitive prices~

IGF-1

 Available at Vitamin Wagon

IGF-1 1oz 23 day supply (also available in 2 oz)

IGF-1 blood levels decrease after the age of thirty, similar to decreases in human growth hormone. Aging and environmental toxins are often accompanied by lowered physical and mental functioning due to poorly coordinated cell-to-cell communication. Balancing IGF-1 and hGH feedback loops can be done safely and effectively, increasing the quality of life and sense of well-being.

 Increase:

• Energy & Stamina

• Strength & Muscle Tone

• Memory & Mental Clarity

• Positive Mood & Sense of Well-being

 Decrease:

• Appetite

• Nervousness, Anger & Anxiety

• Aches and Pains

Product Highlights:

• 23 day supply
• Increase lean muscle
• Increased energy and endurance
• Can improve our cardiac system, improve sleep, memory retention and weight loss
• Assist with anti-aging
• May improve sexual performance

Directions:

ADULTS:
Take 5 - 7 drops 3 times daily. For optimal results, place drops under the tongue or swish around mouth fr 1 minute. Do not consume food or liquid (except water) for at least 20 minutes before use. NOTE:  IGF-1 can lower blood glucose. If this is an issue, it is best to take 20 - 60 minutes after meals.

Alternate Dosage: Take as directed by your healthcare professional.

As with any drug, if you are pregnant or nursing, seek the advice of a healthcare professional before using this product.

Ingredients:

Homeopathic Formula USP Ingredients
Active: Homeopathic recombinant Human Insulin-like Growth Factor 1 (igf-1) 30C
Inactive: Purified Active Water with 20% ethyl alcohol

Always seek of your physician or other qualified, licensed health professional.
*These statements have not been evaluated by the Food and Drug Administration.
Products and information on this site are not intended to diagnose, treat, cure or prevent and disease.

~Vitamin Wagon carries quality products at competitive prices~

Boluoke - Canada RNA

 

 

Available at Vitamin Wagon

 

 

Boluoke is a new enzyme supplement known to benefit the circulation and characteristics of the blood. It is a promising new tool for those seeking to treat heart disease or proactively prevent it.  Boluoke contains the enzyme lumbrokinase, which has been shown to assist with the breakdown of fibrin, a protein involved in blood clotting. It has proven valuable in acute, sub-acute, and chronic conditions associated with clotting tendencies and poor circulation. Supplementing with Boluoke helps to maintain an optimal environment for healthy circulation. It is also recommended for people using hormone supplementation or birth control pills.

 

Boluoke® is the only lumbrokinase that has been thoroughly researched and its enzymatic strength is standardized. Other lumbrokinase products currently on the market often are citing Boluoke’s credentials and research, and are not disclosing the enzymatic strength of their lumbrokinase. On the raw material market, the price of lumbrokinase can vary by up to 15 folds, and the enzymatic strengths of various lumbrokinase also differ greatly.

 

In addition, lumbrokinase is a preparation containing multiple enzyme fractions, and the extraction and purification methods would determine the final compositions of the various enzyme fractions. Therefore, different products would have different lumbrokinase compositions and cannot be considered the same. This is also the reason why Boluoke does not significantly affect blood tests like prothrombin time (PT) or activated partial thromboplastin time (aPTT), while other lumbrokinase products may affect the test results.

 

Boluoke (lumbrokinase) is the only fully researched oral enzyme on the market supporting a healthier blood state, and it shows great promise in supporting a healthy coagulation/fibrinolysis balance in the body.  Coagulation system is a complicated and highly regulated system. Modern lifestyles often tip the balance towards hypercoagulation and rarely towards hypocoagulation. For most people, Boluoke can support the body in keeping the system in a more balanced state. Some practitioners are also recommending Boluoke for those who choose to be on hormone replacement therapy or birth control pills, and for those who could not tolerate standard preventative pharmaceutical drugs.

 

Suggested Use: 
Take 1 capsule one to three times daily 30 minutes before meals.
If maximal fibrinolytic effect is desired, take 2 capsules three times daily 30 minutes before meals for 3 weeks or consult your physician for optimal dosage.

Warning: Please consult your physician before taking this product or any other health supplement, especially if you are on any prescription medicine, are pregnant or have bleeding risks. People with known allergy to lumbrokinase should not take this product.

SUPPLEMENT FACTS:
SERVING SIZE: 1 TABLET

Ingredient

Amount Per Serving

% Daily Value

Lumbrokinase (Proprietary earthworm protein extract)

20 mg

*

*Daily Value not established.

Other Ingredients:  Gelatin, starch

Store in a cool, dry place away from sunlight.

KEEP OUT OF THE REACH OF CHILDREN.

These statements have not been evaluated by the FDA.
This product is not intended to diagnose, cure or prevent disease.

 

~Vitamin Wagon carries quality products at competitive prices~

Wobenzym N - Mucos Pharma

Available at Vitamin Wagon
 



Wobenzym N (Available in 200, 400 and 800 count) is the authentic systemic enzyme formula trusted by millions worldwide to provide clinically demonstrated support for joint and inflammation health.† First introduced in Germany as a pharmaceutical over 40 years ago, Wobenzym N has been updated but still features the time-tested, synergistic combination of plant-based enzymes, pancreatic enzymes and antioxidants. These powerful yet delicate enzymes are protected by a vegetable-based enteric coating which ensures optimal absorption and utilization in the blood stream.

Years of Research and Validation
The exact formulation found in Wobenzym N has been featured in six human clinical studies with 2,489 patients studied. When you read that Wobenzym N provides temporary relief from everyday aches, pains and muscle soreness due to everyday activity, increased flexibility and mobility, and promotes a normal inflammation response and supports joint and tendon health, you know that these results have been clinically studied.† Since Wobenzym N became available in Europe in the 1960s, over 29 million people have taken the product. Millions of ordinary people seeking temporary relief have found an answer in Wobenzym N.†

The Far-Reaching Benefits of Wobenzym N
Wobenzym N is a unique blend of systemic enzymes that provides temporary relief from aches, pain and muscle soreness due to everyday activity, supports the body’s natural inflammation response, and leads to increased flexibility and mobility and supports overall joint and tendon health as well.†   Enzymes are fascinating essential biological catalysts that are involved in almost every single process in the body. They initiate millions of chemical reactions every second in the human body. It is easy to see why supplementing with systemic enzymes can have far-reaching benefits to the human body.†  The enzyme blend in Wobenzym N contains the following, clinically studied enzymes: pancreatin, papain, bromelain, trypsin, and chymotrypsin. Each one of these is a protease, which simply means that they break down proteins.†  There are certain proteins in the body that stimulate and others that repress inflammation. Under normal circumstances, your body balances the two. The systemic enzymes in Wobenzym N support that balancing process, assisting normal inflammation response that in turn, leads to temporary relief from everyday activity-related aches and pains.†

 

 

And of course, Wobenzym N tablets are enteric coated to ensure that the enzymes are protected and allows them to reach the small intestine, where absorption occurs and they can be accessed by the body.

 

The key benefits of Wobenzym N include:
Supports the Body’s Natural Inflammation Response†
Increases Flexibility and Mobility†
Supports Joint and Tendon Health†
Temporary Relief from Aches, Pains and Muscle Soreness due to Everyday Activity† 

Wobenzym N works holistically — throughout your entire body — to support your body’s natural response to inflammation.† While inflammation in the body is a normal and natural response, the aches, pains and muscle soreness that often accompany it can keep you from living the active lifestyle you desire. Experiencing extraordinary health is all about helping the body achieve homeostasis — a dynamic state of balance.

If you want to take control of your life and live it on your terms, choose the brand that has been trusted by millions worldwide for decades — choose Wobenzym N.

^†These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.

 

 

~Vitamin Wagon carries quality products at competitive prices~