Ubiquinol-QH with VESIsorb Technology - Douglas Laboratories

Available at Vitamin Wagon

Ubiquinol-QH with VESIsorb Technology

Douglas Laboratories


DESCRIPTION Ubiquinol-QH, provided by Douglas Laboratories, is a softgel containing 100 mg of natural ubiquinol in a patented, naturally self-assembling nano-colloid system called VESIsorb® technology for enhanced absorption. 

FUNCTIONS Ubiquinol is the biologically reduced form of ubiquinone, also known as coenzyme Q10. Ubiquinone can be converted by the body into ubiquinol. While supplemental ubiquinone plays a valuable role in health and can be utilized by the body, recent studies indicate that as people age, the body's ability to convert ubiquinone to ubiquinol begins to decline. Since this nutrient plays critical roles in antioxidant, energy and cardiovascular function, ubiquinol may be of special importance for older adults looking to support normal aging and cardiovascular function. In one study, older adults with suboptimal cardiovascular function were found to be able to support and maintain their cardiovascular function with supplementation of ubiquinol. 

Our Ubiquinol-QH is unique among other ubiquinol products as it utilizes the patented VESIsorb® technology to deliver ubiquinol. When mixed with an aqueous system, this patented technology results in the formation of a nano-colloid containing solubilized ubiquinol. This association colloid delivery system contains a highly uniform distribution of droplets that are less than 100 nm in diameter. The size and structure of these droplets allow for enhanced solubility and absorption of ubiquinol. The formation of the colloidal system upon contact with an aqueous environment (such as the lumen of the intestine) enables the solubilized ubiquinol to more easily diffuse across the unstirred water layer that is present between the enterocyte and the lumen of the intestine. One can demonstrate the enhanced solubility of the ubiquinol contained in Ubiquinol-QH by placing a capsule in warm water. Once the capsule opens, the contents can be easily mixed with the water, resulting in the formation of the association colloid. There is no separation of oil and water phases as is typical with more traditional delivery systems. 

INDICATIONS Ubiquinol-QH may be a useful dietary supplement for individuals wishing to support cardiovascular function.

FORMULA (#201899) 1 softgel Contains:
Vitamin E (as d-alpha tocopheryl) . . . .10 IU 
Ubiquinol . . . . . . . . . . . . . . . . . . . . . . 100 mg (Kaneka QH™ reduced form of CoQ10) 

Other ingredients: 
Gelatin (bovine, capsule), medium chain triglycerides, polysorbate 80, polyglycerol fatty acid esters, glycerin and caramel color.

VESIsorb is a registered trademark of Vesifact AG. Kaneka QH™ is a trademark of Kaneka Corporation.

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Real Niacin - Doctor's Best

Available at Vitamin Wagon

Real Niacin
8 Hour Extended Release
No/Low Flush

Doctor's Best

Suitable for vegetarians

• Science-based nutrition
• Dietary supplement
• Promotes cardiovascular health
• 8-hour extended-release
• No/low flush

Real Niacin provides niacin in an 8-hour extended-release form that enables you to enjoy the health benefits of niacin without experiencing the uncomfortable skin flushing that commonly accompanies other forms of niacin.*
Niacin comprises approximately 200 coenzymes that play pivotal roles in metabolism and energy production within the body.* 


Additionally, research suggests that niacin, in combination with a well-balanced diet, may help to maintain healthy cholesterol levels that are already within the normal range.*
Niacin, also known as vitamin B3 or nicotinic acid, supports more than 500 enzymatic reactions that play pivotal roles in metabolism, energy production, and healthy aging. Real Niacin provides a considerable amount of nicotinic acid combined with a proprietary wax-coated technology to yield an 8-hour extended-release tablet that greatly reduces the chance of experiencing the uncomfortable skin flushing that commonly accompanies brands of this vitamin that don’t feature a extended-release mechanism.


Real Niacin provides an 8-hour extended-release tablet that enables more people to access the health-supportive aspects of niacin with less chance of experiencing the uncomfortable skin flushing that commonly accompanies the unspecialized niacin in immediate-release (IR) forms of the vitamin. Release of the eicosanoid prostaglandin D2 from skin cells is believed to be behind the skin flushing that may occur with niacin use. This “prickly heat” phenomenon results in a sensation of warmth, reddening, and/or tingling anywhere from 15 to 120 minutes after consumption of a large dose, often felt on the head, neck, and shoulders for up to an hour. Although flushing is a non-allergic reaction producing no permanent harm to the body, it is the major reason for discontinued use of niacin—thereby preventing many individuals from experiencing the potential benefits of supplementation. When taken as directed, extended-release formulas similar to Real Niacin have been shown to decrease the potential of flushing.

Supplement Facts
Serving Size: 1 tablet

Suggested Adult Use:
Take one tablet with food, one to two times daily or as directed by your physician.

Serving per container: 120 servings

Amount Per Serving                                % DV    
Niacin                                     500 mg        2500%
(as nicotinic acid)
 
† Daily Value not established.

Other Ingredients: Stearic acid, carnauba wax, magnesium stearate (vegetable source), silica.

Caution: Temporary flushing, itching, or warming of the skin may occur upon initial use.

If you are under medical supervision, have liver dysfunction, gout, or are pregnant or nursing, consult your physician before taking this product.

Contains nothing other than listed ingredients.

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CHOLINE ALFOSCERATE - Advanced Orthomolecular Research

Available at Vitamin Wagon

CHOLINE ALFOSCERATE Advanced Orthomolecular Research


Choline Alfoscerate is L-a-glyceryl phosphorylcholine (GPC),a key brain cell membrane phospholipid and cholinergic precursor. It is a source of choline for the synthesis of the neurotransmitter acetylcholine, with a greater ability to penetrate the blood-brain barrier than conventional choline sources. More importantly, Choline alfoscerate has been experimentally demonstrated to reduce or reverse age-related structural changes in the frontal cortex and hippocampus and induced functional deficiencies of the cholinergic system. Research supports choline alfoscerates ability to support healthy brain function and the release of somatotrophin (hGH).

The aging brain's cholinergic function is impaired at several points, all of which affect mental performance:

• The ability of the brain to take in necessary raw materials.
• The loss of balance in key cholinergic enzymes.
• The loss of choinergic neurons.

Choline alfoscerate (al-FOSS-er-ate), or alpha-glycerylphosphorylcholine (GPC), is a phospholipid - a complex fatty substance containing phosphorus, like phosphatidylserine and phosphatidylcholine - and is an important building block in the construction of nerve cell membranes. After completing an analysis of thirteen published clinical trials, involving over 4000 patients, a group of Italian scientists concluded that "The stated therapeutic usefulness of Choline Alfoscerate in the relief of cognitive symptoms, such as memory and attention impairment, differentiates [it] from cholinergic precursors used in former clinical trials", such as choline, lecithin, or phosphatidylcholine. The reason, as evidence now suggests, is that the effects of this versatile nutrient extend well beyond its role as a mere choline source: choline alfoscerate supports the restoration of a whole spectrum of youthful cholinergic functions.

Weak Link 1: Decreased Choline Uptake
Choline alfoscerate is a rapidly absorbed source of choline, which easily enters the brain. GPC raises free plasma choline more rapidly than other uncharged choline precursors. Because it is a phospholipid - the same sort of material of which the brain and Blood-Brain Barrier (BBB) are made - Choline Alfoscerate does not carry the electrical charge of regular choline, and so freely crosses the blood-brain barrier. The choline from Choline Alfoscerate is incorporated into brain phospholipids within 24 hours of absorption.

Weak Link 2: Enzyme Imbalances
The brain makes acetylcholine using an enzyme known as choline acetyltransferase. As we get older, ChAT activity goes down, while the activity of enzymes that break down chat goes up. As a result, aging brains make less acetylcholine from the choline available to them, while they tear acetylcholine down more quickly. Animal studies suggest that Choline Alfoscerate may also improve the levels of ChAT.

Weak Link 3: Brain Drain
This is perhaps the most serious issue facing the aging brain: the cholinergic neurons of the brain simply wither away with age. The number of neurons declines, and those neurons that remain literally shrink, becoming less well-connected to the rest of the brain. This decay is made all the worse by the fact that the ability of the surviving cholinergic neurons to release and respond to ACh is also impaired with age!

There are two main reasons for this loss of function. First, the composition of the nerve cell membrane is altered with age, becoming less flexible and responsive. This makes it harder for the neuron which is sending the signal to release the ACh messenger, and harder for the receiving neuron to pick it up. Choline alfoscerate restores membrane and fluidity responsiveness, both because having more Choline Alfoscerate in the membrane directly makes the membrane more fluid, and perhaps because Choline Alfoscerate inhibits an enzyme (lysophospholipase) that breaks down some brain phospholipids.

Second, some of the receptors to which ACh is designed to bind - the "mailbox" to which they are addressed - also decline with age. This is especially true of the muscarinic-type-1 (M1) receptors - the ones involved in higher mental function. While most other cholinergic receptors remain plentiful throughout life. Fortunately, Choline Alfoscerate selectively restores the number of memory-specific cholinergic receptors.

Even more incredibly, animal studies show that Choline Alfoscerate actually increases the number of cholinergic neurons as well. In addition, Choline Alfoscerate may reverse the atrophy of existing cholinergic neurons, since studies show that Choline Alfoscerate increases the number of receptors for nerve growth factor (NGF). Supplying NGF to old monkeys clearly reverses cholinergic neuron atrophy, restoring the number and size of these neurons to more youthful levels.

Controlled Trials: It Works
In one controlled trial in victims of vascular dementia, greater improvements on several measures of cognitive function were seen amongst those patients treated with Choline Alfoscerate than in those given another choline precursor. The differences were statistically significant, and both patients and physicians rated the results with GPC more satisfactory.

Another controlled trial in Alzheimer's disease compared Choline Alfoscerate to acetyl-L-carnitine (ALCAR), a nutrient already proven to slow the progression of AD in younger patients. Most behavioral and mental function test results showed improvement in the Choline Alfoscerate group - and the improvements were greater than those seen in the ALCAR group.

Yet another trial monitored the progress of 2044 patients who were being treated with Choline Alfoscerate after recent strokes or transient ischemic attacks (TIAs - sometimes called "mini-strokes"). Statistically significant improvements were seen on several scales of cognitive performance, such that the Mini Mental State (MMS) score was found to be within the normal range, Chrichton Rating Scale (CRS) decreased by a significant 4.3 points, and the Global Deterioration Scale scores indicated "no cognitive decline" or "forgetfulness" rather than clinical mental impairment.

There is also a hint that Choline Alfoscerate may prove of use in Parkinson's disease (PD). PD is characterized by reductions in the production of the neurotransmitter dopamine in an area of the brain called the substantia nigra. This leads to a loss of motor control, typically manifesting in facial ticks or tremors, dry mouth, and a "masklike" facial expression. In laboratory animals, measures of dopaminergic activity were enhanced by GPC treatment.

60 Vegi-Caps 100% Vegetarian
______________________________________________
SUPPLEMENT FACTS:
Serving Size: 1 Capsule %DRI
______________________________________________
L-a-glyceryl phosphorylcholine ............. 250 mg *
______________________________________________

*Dietary Reference Intake not established.
Other ingredients: microcrystalline cellulose. Capsule: hypromellose, sorbitol, silicon dioxide, water.

AOR guarantees that no ingredients not listed on the label have been added to the product. Contains no wheat, gluten, corn, nuts, dairy, eggs, fish or shellfish.

Suggested Use
Take two to four capsules daily, or as directed by a qualified health care practitioner.

Main Applications
As reported by literature:
Support in Alzheimer's disease
Cognitive support
Infant brain development

Source
Purified from lecithin.

Pregnancy / Nursing
Safe at 1-2 capsules per day.

Cautions
None known.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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VITALZYM CARDIO - World Nutrition Inc.

Available at Vitamin Wagon

VITALZYM CARDIO 

 World Nutrition Inc.

Overview:

Vitalzym Cardio includes the same great benefits as our Vitälzȳm hybrid formula (systemic and digestive), while also providing cardiovascular support for a happy, healthy heart. Vitalzym Cardio harnesses the cardiovascular benefits of Vitalzym with nattokinase – a rich, all-natural enzyme shown to help support blood mobility and heart function. Vitalzym Cardio also contains CoQ10 – a powerful anti-oxidant that is naturally produced by your body – and magnesium, which have both been shown to have help maintain healthy heart function. Vitalzym Cardio gives your bloodstream the cleansing that it needs to perform at optimal health levels.*

Vitalzym Cardio's proprietary blend also contains Serrapeptase, Bromelain, Papain, Lipase, Protease, Rutin, Amylase and Amla.

Like World Nutrition’s other powder-based products,Vitalzym Cardio capsules begin to breakdown in the stomach providing digestive support while the buffer enteric-coated Serrapeptase survives the stomach and breaks down in the small intestine, where it absorbed into the bloodstream and distributed throughout the body for systemic support.

Vitalzym Cardio is available in a 300-count bottle, and can be purchased through health care practitioners, retailers and online stores. For a listing of authorized retailers where you can safely purchase Vitälzӯm Cardio, click here.

Vitalzym Cardio

What Can I Use Vitazym Cardio For?

Vitalzym Cardio is specially engineered to help support:

• Healthy blood viscosity and fibrin levels*
• Healthy heart function*
• Healthy circulation*
• Healthy gastrointestinal & digestive function*
• And so much more!

Quick Facts

• Nattokinase, COQ10, and Magnesium in addition to the Vitälzȳm blend
• All-natural powerful antioxidants in a vegetarian formula

Suggested Use

As a dietary supplement, take one (1) capsule three times daily or as directed by your healthcare provider. Take capsules at least 30 minutes before a meal, 60 minutes after a meal or any time in between.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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