Glutathione (GSH) is often referred to as the body's master antioxidant. Composed of three amino acids - cysteine, glycine, and glutamate - glutathione can be found in virtually every cell of the human body. The highest concentration of glutathione is in the liver, making it critical in the body's detoxification process.
Glutathione is also an essential component to the body's natural defense system. Viruses, bacteria, heavy metal toxicity, radiation, certain medications, and even the normal process of aging can all cause free-radical damage to healthy cells and deplete glutathione. Glutathione depletion has been correlated with lower immune function and increased vulnerability to infection due to the liver's reduced ability to detoxify.
Advantages of Essential GSH™
What Makes Essential GSH™ Different?
• No alcohol
• Pharmaceutical grade base
• Proven cell absorption via in vivo and in vitro exposure
• Easily adjustable dosages – easy to measure
• Contains essential phospholipids (no hydroxylated lecithin)
• Gluten/casein free
• SCD compliant
In Vitro Test Results
L2 cells were exposed to 2.5% Essential GSH™ and intracellular glutathione was measured after 30 minutes, 1 hour, 2 hours, 3 hours, and 4 hours. Intracellular glutathione content was measured via the spectrophotometric recycling assay, normalized to total cellular protein.
Results clearly indicate that intracellular glutathione levels increased after exposure to Essential GSH™, peaking at 2 hours with over a 2-fold increase. The transient action of the increased glutathione remains unknown, although repression of the endogenous glutamate-cysteine ligase (GCL) enzyme through GSH-feedback inhibition may be a likely reason.
Tests performed by:
Dale Dickinson, PhD
Assistant Professor
Department of Environmental Sciences
University of Alabama at Birmingham
Essential GSH with BioGlute Complex is a breakthrough liquid formulation uniquely designed to increase the systemic bioavailability of glutathione, via a liposomal-based delivery. This unique formulation contains a pharmaceutical grade glutathione with essential phospholipids, while containing no alcohol or glycerine.
Glutathione is a peptide and an anti-oxidant naturally produced in the body. It is important to good health and long life. Levels may drop as a result of oxidative stress due to disease, drugs, aging, toxic chemicals, inflammation, and stress in general. Adequate levels of glutathione are necessary to provide important antioxidant protection needed by the cells, to help eliminate toxic metabolic waste products and to support the immune system.
What is a Liposome?
Derived from lecithin, a liposome is a microscopic fluid-filled pouch with walls identical to the phospholipids that make up the human cell membranes. The outer wall of the liposome is fat solublewhile the inside is water-soluble. This combination enables liposomes to be readily absorbed, allowing for systemic availability of the water-soluble materials that would otherwise not be absorbed into the body. The administering of therapeutic compounds via liposomal technology has been effective in many areas. L2 cells were exposed to 2.5% Essential GSH and intracellular glutathione was measured after 30 minutes, 1 hour, 2 hours, 3 hours, and 4 hours. Intracellular glutathione content was measured via the spectrophotometric recycling assay, normalized to total cellular protein. Results clearly indicate that intracellular glutathione levels increased after exposure to Essential GSH, peaking at 2 hours with over a 2-fold increase. The transient action of the increased glutathione remains unknown, although repression of the endogenous glutamate-cysteine ligase (GCL) enzyme through GSH-feedback inhibition may be a likely reason.
Recommended Servings
For Adults:
As a dietary supplement, take one teaspoonful (approx. 430mg) or as otherwise directed by your physician or health care professional.
For Children:
Please consult with your child’s physician before use.
Essential Nutraceuticals™ recommends 1/8 - ¼ of a teaspoon (approx. 55-108mg) for every 30lbs of the child’s weight, twice a day.
Directions:
Gently invert before using.- Do not shake vigorously.
Mix one serving in water or juice of choice, and drink promptly.
Store at room temperature or in the refrigerator.
