Available at Vitamin Wagon
Advanced Orthomolecular Research
100% Vegetarian
Hydroxycobalamin is a unique form of vitamin B12, which is more readily converted into the coenzyme forms than conventional cyanocobalamin. Hydroxycobalamin also readily binds body stores of cyanide, unlike conventional cyanocobalamin, which already includes this ion in its structure.
When you take a regular B12 (cyanocobalamin) supplement, the body must first convert its B12 into Hydroxycobalamin order to form the B12 coenzymes. This involves the removal and detoxification of the cyanide molecule, followed by biochemical reduction to a less oxidized (+1 valence) state, and then the enzymatic conversion of the reduced cobalamin into one of two metabolically active coenzyme forms. By taking a preformed Hydroxycobalamin supplement, you can skip over this first biochemical stumbling block, allowing for unhampered formation of adenosylcobalamin and Methylcobalamin.
Methylcobalamin or Hydroxycobalamin?Because the body can interconvert the two B12 coenzymes, and because the body stores adenosylcobalamin but not Methylcobalamin, an adequate supply of Methylcobalamin usually ensures that you'll have plenty of adenosylcobalamin, too - but not vice-versa. Because of this fact, and because of the powerful neuroprotective effects of Methylcobalamin, a fully-formed Methylcobalamin supplement is the best choice for most people.
One key exception is persons with known or suspected cyanide toxicity, where Hydroxycobalamin has an unique role to play. Hydroxycobalamin helps the body to rid itself of cyanide, both by reacting with the toxin to form cyanocobalamin (which can then be excreted) and by enhancing the detoxification of cyanide through its conversion into the less toxic thiocyanate. In isolated human cells, Hydroxycobalamin penetrates cyanide-laden cells and detoxifies the toxin directly. Hydroxycobalamin has a long history of intravenous use for acute, life-threatening cyanide toxicity (such as during industrial disasters) and is approved for this use in many European countries. At lower doses, oral Hydroxycobalamin increases the urinary excretion of thiocyanate in laboratory animals fed cyanide-containing diets. Sublingual Hydroxycobalamin is an ideal choice for a B12 supplement in persons concerned with chronic, low-level cyanide toxicity.
60 Sublingual Lozenges100% Vegetarian
SUPPLEMENT FACTS:
Serving Size: 1 Lozenge
| Hydroxycobalamin | 1000mcg |
Non-medicinal ingredients: silicon dioxide, sorbitol, magnesium stearate.
AOR guarantees that no ingredients not listed on the label have been added to the product.
Contains no wheat, gluten, nuts, dairy, soy, eggs, fish or shellfish.
Suggested Use
Take one lozenge under the tongue daily with food, or as directed by a qualified health care practitioner.
Main Applications
• Pernicious anemia.
• Superior B12 supplement.
• Cyanide toxicity.
Source
Biological fermentation.
Pregnancy / Nursing
Safe.
Cautions
None.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
The information and product descriptions appearing on this website are for information purposes only, and are not intended to provide medical advice to individuals. Consult with your physician if you have any health concerns, and before initiating any new diet, exercise, supplement, or other lifestyle changes.
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