High Dose R-Lipoic Acid - Advanced Orthomolecular Research

Available at Vitamin Wagon

High Dose R-Lipoic Acid from AOR provides a high dose of powerful antioxidants for the maintenance of good health.

AOR’s High Dose R-Lipoic Acid provides only the natural ‘R’ form of this vital antioxidant produced in the body, unlike most alpha-lipoic acid supplements which also contain equal amounts of the synthetic, inactive ‘S’ form. *

Product Code	Size	Servings	Vegetarian
AOR08289	60 Vegi-Caps	60 Servings	100% Vegetarian

Supplement Facts
Serving Size: 1 Capsule	Amount Per Capsule	% Daily Value
Sodium (from R-Lipoic Acid sodium salt	30 mg	1.2%
R-Lipoic Acid (sodium salt)	300 mg	†
† %Daily Value not established Other ingredients: microcrystalline cellulose, silicon dioxide, sodium stearyl fumarate. Capsule: hypromellose.

AOR™ guarantees that there is not more than 14 mg of S-lipoic acid per capsule, and that no ingredients not listed on the label have been added to the product. Contains no wheat, gluten, corn, nuts, dairy, soy, eggs, fish, shellfish or any animal byproduct.

Suggested Use: Take 1 capsule twice daily with/without food, or as directed by a qualified health care practitioner. Consult a health care practitioner prior to use if you are pregnant or breastfeeding.

Cautions:
Consult a health care practitioner prior to use if you have diabetes.

Pregnancy/Nursing:
Consult a health care practitioner

Source:
Pharmaceutical Synthesis 

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

 The information and product descriptions appearing on this website are for information purposes only, and are not intended to provide medical advice to individuals.
Consult with your physician if you have any health concerns, and before initiating any new diet, exercise, supplement, or other lifestyle changes.

~Vitamin Wagon carries quality products at competitive prices~

PEAK K2 - Advanced Orthomolecular Research

Available at Vitamin Wagon

PEAK K2 Veggie Caps

Advanced Orthomolecular Research

Peak K2 is menatetrenone (MK-4), a form of vitamin K2 made in the body from phylloquinone (vitamin K1) and distinct from the menaquinones made by probiotic bacteria. Available science indicates that vitamin K2 – and especially menatetrenone – is greater than Vitamin K1 in maintaining the health of the bones and vascular system. Clinical trials have proven that high-dose vitamin K2 does not cause excessive or abnormal blood clotting, although it will interfere with “blood thinning” medications.

ADULT DOSAGE: Take one to three capsules daily with food, or as directed by a qualified health care practitioner.

Supplement Facts
Serving Size: 1 Capsule	Amount Per Capsule	% Daily Value
Menatetrenone (Vitamin K2 [MK-4])	15mg	18,750%
*Dietary Reference Intake not established. Other ingredients: microcrystalline cellulose. Capsule: hypromellose, water.

AOR™ guarantees that no ingredients not listed on the label have been added to the product. Contains no corn, wheat, gluten, nuts, dairy, soy, eggs, fish, shellfish or any animal byproducts.

Main Applications
As reported by literature:
• Bone health
• Brain health
• Cardiovascular function

Source
Solanesol (from Nicotiana tabacum).

Pregnancy / Nursing
Do not use.

Cautions
• Clinical trials have documented that menatetrenone does not induce hemostatic activation. However, it will interfere with the activity warfarin (Coumadin®) and possibly other anticoagulant ("blood thinning") medications. Patients prescribed anticoagulants must not take this supplement.

 • STORE IN A COOL DARK PLACE. HARMLESS CLUMPING MAY OCCUR AT TEMPERATURES EXCEEDING 35C

Menatetrenone Vitamin K is an essential nutrient, best known for its role in blood clotting. Plants make one form of vitamin K (phylloquinone, or vitamin K1) for their use. But your body doesn't use all of the K1 in your diet "as is." Instead, the body converts some of this plant form of the vitamin into a different vitamin K molecule: Menatetrenone, or MK-4, a form of vitamin K2. Tissues vary in their vitamin K needs, and it's become clear that some tissues have a specific need for Menatetrenone, which is not met by phylloquinone. For some purposes (like blood clotting), phylloquinone works fine; but extensive evidence shows that Menatetrenone has unique effects on bone health not shared by phylloquinone. •Fracture victims' levels of Menatetrenone are more depressed than are their levels of phylloquinone. •Areas where more K2 is consumed in the diet have lower fracture rates. Menatetrenone inhibits the resorption (teardown) of bone caused by the local cellular messenger prostaglandin E2 (PGE2). The same concentration of phylloquinone has no effect. Menatetrenone also cuts down on the bone cells' formation of PGE2 in the first place. Menatetrenone is able to reduce the creation of osteoclasts (cells involved in the teardown of bone tissue) out of early cell types - but again, phylloquinone has no such power. Menatetrenone, but not phylloquinone, actually increases the programmed cell death ("apoptosis") of existing osteoclasts. Menatetrenone strengthens the bone-building legions of the osteoblasts (cells involved in the manufacture of new bone), mildly increasing both their numbers and their activity. Over the course of the last decade, at least sixteen clinical trials have been performed using Menatetrenone, and every single one has found that K2 supplements protect bone health. Menatetrenone not only slows, halts, or even reverses loss of bone mass: it dramatically reduces your risk of suffering a fracture. •In one trial, women who took an ultra-high dose Menatetrenone supplement for 24 weeks increased their bone mineral density by an impressive 2.2%, even as the women taking a placebo (dummy pill) lost 7.31% of their bone density. •In another trial, Menatetrenone was put to the test in a direct comparison against the bisphosphonate drug etidronate (Didrocal®). Menatetrenone preserved bone mass, and also slashed fracture risk by roughly two thirds over the course of two years. •In a third trial, osteoporotic women taking Menatetrenone supplements sustained nearly no bone loss over two years, while cutting fracture risk by 64% as compared with non-supplementing women. The ability of bones to withstand fractures is not just determined by the quantity of bone (as measured by Bone Mineral Density (BMD)), but also by the quality of bone - bone "microarchitecture," including especially "trabecular connectivity." Evidence suggests that Menatetrenone's most important effects are on bone quality, not bone quantity. •Clinical trials have found that Menatetrenone provides as much protection against fracture as drugs that have much more powerful effects on BMD. Clearly, Menatetrenone's bone-protective effects extend to aspects of bone health beyond the BMD numbers. •Menatetrenone provides powerful protection against the loss of trabecular connectivity in laboratory animal models of menopausal osteoporosis. •Menatetrenone supplements increase bone quality in young, healthy animals. To get the amount of Menatetrenone used to produce these effects in clinical trials and experimental studies requires a specific Menatetrenone supplement. •Existing science shows that phylloquinone does not provide the same benefits as Menatetrenone. No clinical trials using phylloquinone supplements have been performed to show reduced fracture risk. •The body's ability to convert phylloquinone into Menatetrenone is limited, flattening out at levels far below what's used in clinical trials. This ability is further reduced with aging. •Very little vitamin K2 exists in the diet, even in the richest food sources. •While the body's friendly bacteria produce some K2, little or none of this K2 is absorbed. Menatetrenone's health benefits extend well beyond the skeletal system. Emerging science is now documenting the role of vitamin K - and specifically of Menatetrenone - in protecting our cardiovascular health, and the health of that all-important organ, the brain. References i. Orimo H, Shiraki M, Tomita A, Morii H, Fujita T, Ohata M. "Effects of menatetrenone on the bone and calcium metabolism in osteoporosis: a double-blind placebo-controlled trial." J Bone Miner Metab 1998; 16(2): 106-12. ii. Iwamoto J, Takeda T, Ichimura S. "Effect of menatetrenone on bone mineral density and incidence of vertebral fractures in postmenopausal women with osteoporosis: a comparison with the effect of etidronate." J Orthop Sci. 2001; 6(6): 487-92. iii. Shiraki M, Shiraki Y, Aoki C, Miura M. "Vitamin K2 (menatetrenone) effectively prevents fractures and sustains lumbar bone mineral density in osteoporosis." J Bone Miner Res. 2000 Mar; 15(3): 515-21. iv. Geleijnse JM, Vermeer C, Jurgers LJ, Grobbee DE, Pols HA, Witteman JC. "Inverse association of dietary vitamin K-2 intake with cardiac eventsand aortic atherosclerosis: the Rotterdam Study." Thromb Haem. 2001 Jul; 85(Suppl): AbsP473. v. Allison AC. "The possible role of vitamin K deficiency in the pathogenesis of Alzheimer's disease and in augmenting brain damage associated with cardiovascular disease." Med Hypotheses. 2001 Aug; 57(2): 151-5. vi. Vermeer C. "Prevention of arterial calcification by vitamin K2." In Miki T (ed). "Vitamin K: A Conference Record. Renewing Bone Metabolism." 2000; Tokyo: Intermedd Inc, 2-21. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. The information and product descriptions appearing on this website are for information purposes only, and are not intended to provide medical advice to individuals. Consult with your physician if you have any health concerns, and before initiating any new diet, exercise, supplement, or other lifestyle changes. ~Vitamin Wagon carries quality products at competitive prices~

High Dose R-Lipoic Acid - Advanced Orthomolecular Research

Available at Vitamin Wagon

High Dose R-Lipoic Acid from AOR provides a high dose of powerful antioxidants for the maintenance of good health.

AOR’s High Dose R-Lipoic Acid provides only the natural ‘R’ form of this vital antioxidant produced in the body, unlike most alpha-lipoic acid supplements which also contain equal amounts of the synthetic, inactive ‘S’ form. *

Product Code	Size	Servings	Vegetarian
AOR08289	60 Vegi-Caps	60 Servings	100% Vegetarian

Supplement Facts
Serving Size: 1 Capsule	Amount Per Capsule	% Daily Value
Sodium (from R-Lipoic Acid sodium salt	30 mg	1.2%
R-Lipoic Acid (sodium salt)	300 mg	†
† %Daily Value not established Other ingredients: microcrystalline cellulose, silicon dioxide, sodium stearyl fumarate. Capsule: hypromellose.

AOR™ guarantees that there is not more than 14 mg of S-lipoic acid per capsule, and that no ingredients not listed on the label have been added to the product. Contains no wheat, gluten, corn, nuts, dairy, soy, eggs, fish, shellfish or any animal byproduct.

Suggested Use: Take 1 capsule twice daily with/without food, or as directed by a qualified health care practitioner. Consult a health care practitioner prior to use if you are pregnant or breastfeeding.

Cautions:
Consult a health care practitioner prior to use if you have diabetes.

Pregnancy/Nursing:
Consult a health care practitioner

Source:
Pharmaceutical Synthesis 

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

 The information and product descriptions appearing on this website are for information purposes only, and are not intended to provide medical advice to individuals.
Consult with your physician if you have any health concerns, and before initiating any new diet, exercise, supplement, or other lifestyle changes.

~Vitamin Wagon carries quality products at competitive prices~

T-100 - Advanced Orthomolecular Research

Available at Vitamin Wagon

T-100^TM  (3-Pack)  each bottle contains 60 Vegi-caps

 Advanced Orthomolecular Research

T-100 is a glandular support formulation for the thyroid.

Lyophilized thyroid, adrenal, pituitary, spleen and thymus gland tissue extracts are abundantly rich sources of enzymes, polypeptides, amino acids and other nutrients that support the ability of the glands to increase their own hormone production. The use of such glandular extracts to address the symptoms of hypothyroidism - as well as hyperthyroidism - is particularly well established in homeopathic and naturopathic medical circles.

T•100 also provides nutrients necessary for thyroid function, non-thyroid glandulars to support the integrated functioning of the endocrine system, and balancing homeopathics for homeostatic regulation.

SUPPLEMENT FACTS:
Serving Size: 1 Tablet

		% DRI
Thyroid glandular (Thyroxine free) ‡	100mg	†
Adrenal glandular ‡	50mg	†
Pituitary glandular ‡	15mg	†
Spleen glandular ‡	5mg	†
Thymus glandular ‡	5mg	†
L-Tyrosine	30mg	†
Dulse (Rhodymenia palmetta)	400mg	†
Bladderwrack (Fucus vesiculosus)	15mg	†
Irish Moss (Chondrus crispus)	40mg	†
Calcarea fluorica (potentized)	4X	†
Lycopus virginicus (potentized)	4X	†

‡ Lyophylized glandular from free-range, pasture-fed, New Zealand bovine livestock not administered routine antibiotics or rBGH. Absolutely guaranteed free of bovine spongiform encephalopathy (BSE/ "mad cow disease"). †Daily value not established.

Other ingredients: microcrystalline cellulose, gum acacia, magnesium stearate, stearic acid and silicon dioxide.

AOR^TM guarantees that no ingredients not listed on the label have been added to the product. Contains no wheat, gluten, corn, nuts, dairy, soy, eggs, fish or shellfish.

Suggested Use: Take one or two tablets per day with food, or as directed by a qualified health care practitioner.

Main Applications:-Thyroid gland support
-Hypothyroidism

Source: Multi-source

Pregnancy/Nursing:     Do not Take

Cautions:
None Known

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

The information and product descriptions appearing on this website are for information purposes only, and are not intended to provide medical advice to individuals. Consult with your physician if you have any health concerns, and before initiating any new diet, exercise, supplement, or other lifestyle changes.  

~Vitamin Wagon carries quality products at competitive prices~

Strontium Support II - Advanced Orthomolecular Research

Available at Vitamin Wagon

Strontium Support II (NEW 120 VEGI-CAPS) 100% Vegetarian

Advanced Orthomolecular Research

Strontium Support II is an organic, stable strontium form (not to be confused with the radioactive strontium-90 isotope). Strontium is a trace mineral in the diet whose metabolism is closely tied to that of calcium, and which concentrates in the skeletal system, where it supports the function of osteoblasts (the cells which form new bone) while reducing the differentiation and activity of osteoclasts (the cells which resorb old bone). Extensive evidence supports a role for strontium in supporting skeletal health. 

Strontium:The First Bone-Building Supplement!

Bone loss accelerates suddenly in menopausal women because the drop in estrogen levels causes an increase in the resorption (teardown) of existing bone. But resorption is only half of the story. Age-related bone loss is also caused by a decrease in the formation of new bone tissue.

Existing drugs for treating osteoporosis, as well as calcium and vitamin D supplements, work by reducing bone resorption. But they do not support the formation of new bone. These drugs and nutrients increase the mineralization of bone, but they do not help the body to build new bone tissue. And in fact, within weeks of starting use of antiresorptive drugs like Fosamax,® the body's formation of new bone actually decreases. The resulting bone is less prone to fracture, but is not the same as youthful, healthy bone.

Strontium is a mineral found along with calcium in most foods. Research has long suggested that it may be an essential nutrient required for the normal development, structure, function, and health of the skeletal system. Clinical trials going back into the 1940s have supported this conclusion, but recent studies have provided evidence that it can offer unique nutritional support against loss of bone structure and function.

Strontium Support II conveniently provides high-quality strontium at an effective dose in only two capsules. 

Suggested Use
Take one to two capsules daily on an empty stomach, at least two hours before or after food, calcium or milk, but ensure that daily calcium intake is adequate.  Calcium, food and milk products significantly reduce strontium absorption if taken at the same time.

SUPPLEMENT FACTS:

Serving Size:                              2 Capsules      %   DRI

Strontium (from citrate) ..................642 mg           *

Produced through pharmaceutical synthesis

*Daily value not established

Other ingredients: none.

Capsule: Hypromellose

AOR guarantees that no ingredients not listed on the label have been added to the product. Contains no wheat, gluten, corn, nuts, dairy, soy, eggs, fish or shellfish.

Main Applications As reported by literature:
Supports skeletal health.
Source Pharmaceutical synthesis
Pregnancy / Nursing  No studies have been conducted. Best to avoid.

Cautions
Ensure calcium intake is also adequate. Do not take at the same time as calcium supplements. 

Additional Information:

Animal studies have shown that Strontium supplements both decrease bone resorption, and increase the formation of new bone tissue.
• In animal models, Strontium (in various forms, such as chloride, carbonate, gluconate, and lactate) causes "baby" osteoblasts (bone-building cells) to multiply more quickly.
• Bone tissue cultures which are exposed to Strontium synthesize more bone matrix and new bone collagen. The same amount of calcium has no effect on these parameters.
• In bone tissue culture, Strontium reduces bone resorption at concentrations at which calcium has no effect, prevents the resorption caused by excessive parathyroid hormone, and slows the rate at which immature osteoclasts develop.
• Strontium-supplemented diets boost bone strength in experimental animals without a negative impact on bone quality, even at extremely high doses.

Human clinical trials also support Strontium's ability to both support new bone formation and prevent excessive resorption.
• The results of early clinical trials using Strontium (lactate) led researchers to speculate that Strontium increased osteoblast activity.
• Bone biopsies from a small human pilot trial revealed an astounding 172.4% increase in new bone formation activity after six months of Strontium (gluconate) supplementation.
• The bone-building activity of osteoblasts can be measured using bone-specific alkaline phosphatase, while cross-linked N-telopeptide (NTx) and C-telopeptide (CTx) mark the degradation of bone collagen by ravaging osteoclasts.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

The information and product descriptions appearing on this website are for information purposes only, and are not intended to provide medical advice to individuals. Consult with your physician if you have any health concerns, and before initiating any new diet, exercise, supplement, or other lifestyle changes.

~Vitamin Wagon carries quality products at competitive prices~

Pyridoxal-5-phosphate (P5P) - Advanced Orthomolecular Research

Available at Vitamin Wagon

Pyridoxal-5-phosphate (P5P)

Advanced Orthomolecular Research


Pyridoxal-5-phosphate (P5P) is the biologically active form of vitamin B6 that is utilized by the body.
Studies show that P5P is more bioavailable than conventional B6.*

Product Code	Size	Servings	Vegetarian
AOR08173	60 Vegi-Caps	30 Servings	100% Vegetarian

Supplement Facts
Serving Size: 2 Capsules	Amount Per Servings	% Daily Value
Vitamin B6 (Pyridoxal-5’-phosphate)	100 mg	5000%
Other ingredients: microcrystalline cellulose. Capsule: hypromellose, water.

AOR guarantees that no ingredients not listed on the label have been added to the product. 
Contains no wheat, gluten, corn, nuts, dairy, soy, eggs, fish, shellfish or any animal byproduct.

Suggested Use
Take two capsules daily with food, or as directed by a qualified health care practitioner.

Source
Pharmaceutical synthesis

Pregnancy / Nursing
Safe at 100 mg per day

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

~Vitamin Wagon carries quality products at competitive prices~

PEAK K2 - Advanced Orthomolecular Research

Available at Vitamin Wagon

PEAK K2 Veggie Caps

Advanced Orthomolecular Research

Peak K2 is menatetrenone (MK-4), a form of vitamin K2 made in the body from phylloquinone (vitamin K1) and distinct from the menaquinones made by probiotic bacteria. Available science indicates that vitamin K2 – and especially menatetrenone – is greater than Vitamin K1 in maintaining the health of the bones and vascular system. Clinical trials have proven that high-dose vitamin K2 does not cause excessive or abnormal blood clotting, although it will interfere with “blood thinning” medications.

ADULT DOSAGE: Take one to three capsules daily with food, or as directed by a qualified health care practitioner.

Supplement Facts
Serving Size: 1 Capsule	Amount Per Capsule	% Daily Value
Menatetrenone (Vitamin K2 [MK-4])	15mg	18,750%
*Dietary Reference Intake not established. Other ingredients: microcrystalline cellulose. Capsule: hypromellose, water.

AOR™ guarantees that no ingredients not listed on the label have been added to the product. Contains no corn, wheat, gluten, nuts, dairy, soy, eggs, fish, shellfish or any animal byproducts.

Main Applications
As reported by literature:
• Bone health
• Brain health
• Cardiovascular function

Source
Solanesol (from Nicotiana tabacum).

Pregnancy / Nursing
Do not use.

Cautions
• Clinical trials have documented that menatetrenone does not induce hemostatic activation. However, it will interfere with the activity warfarin (Coumadin®) and possibly other anticoagulant ("blood thinning") medications. Patients prescribed anticoagulants must not take this supplement.

 • STORE IN A COOL DARK PLACE. HARMLESS CLUMPING MAY OCCUR AT TEMPERATURES EXCEEDING 35C

Menatetrenone Vitamin K is an essential nutrient, best known for its role in blood clotting. Plants make one form of vitamin K (phylloquinone, or vitamin K1) for their use. But your body doesn't use all of the K1 in your diet "as is." Instead, the body converts some of this plant form of the vitamin into a different vitamin K molecule: Menatetrenone, or MK-4, a form of vitamin K2. Tissues vary in their vitamin K needs, and it's become clear that some tissues have a specific need for Menatetrenone, which is not met by phylloquinone. For some purposes (like blood clotting), phylloquinone works fine; but extensive evidence shows that Menatetrenone has unique effects on bone health not shared by phylloquinone. •Fracture victims' levels of Menatetrenone are more depressed than are their levels of phylloquinone. •Areas where more K2 is consumed in the diet have lower fracture rates. Menatetrenone inhibits the resorption (teardown) of bone caused by the local cellular messenger prostaglandin E2 (PGE2). The same concentration of phylloquinone has no effect. Menatetrenone also cuts down on the bone cells' formation of PGE2 in the first place. Menatetrenone is able to reduce the creation of osteoclasts (cells involved in the teardown of bone tissue) out of early cell types - but again, phylloquinone has no such power. Menatetrenone, but not phylloquinone, actually increases the programmed cell death ("apoptosis") of existing osteoclasts. Menatetrenone strengthens the bone-building legions of the osteoblasts (cells involved in the manufacture of new bone), mildly increasing both their numbers and their activity. Over the course of the last decade, at least sixteen clinical trials have been performed using Menatetrenone, and every single one has found that K2 supplements protect bone health. Menatetrenone not only slows, halts, or even reverses loss of bone mass: it dramatically reduces your risk of suffering a fracture. •In one trial, women who took an ultra-high dose Menatetrenone supplement for 24 weeks increased their bone mineral density by an impressive 2.2%, even as the women taking a placebo (dummy pill) lost 7.31% of their bone density. •In another trial, Menatetrenone was put to the test in a direct comparison against the bisphosphonate drug etidronate (Didrocal®). Menatetrenone preserved bone mass, and also slashed fracture risk by roughly two thirds over the course of two years. •In a third trial, osteoporotic women taking Menatetrenone supplements sustained nearly no bone loss over two years, while cutting fracture risk by 64% as compared with non-supplementing women. The ability of bones to withstand fractures is not just determined by the quantity of bone (as measured by Bone Mineral Density (BMD)), but also by the quality of bone - bone "microarchitecture," including especially "trabecular connectivity." Evidence suggests that Menatetrenone's most important effects are on bone quality, not bone quantity. •Clinical trials have found that Menatetrenone provides as much protection against fracture as drugs that have much more powerful effects on BMD. Clearly, Menatetrenone's bone-protective effects extend to aspects of bone health beyond the BMD numbers. •Menatetrenone provides powerful protection against the loss of trabecular connectivity in laboratory animal models of menopausal osteoporosis. •Menatetrenone supplements increase bone quality in young, healthy animals. To get the amount of Menatetrenone used to produce these effects in clinical trials and experimental studies requires a specific Menatetrenone supplement. •Existing science shows that phylloquinone does not provide the same benefits as Menatetrenone. No clinical trials using phylloquinone supplements have been performed to show reduced fracture risk. •The body's ability to convert phylloquinone into Menatetrenone is limited, flattening out at levels far below what's used in clinical trials. This ability is further reduced with aging. •Very little vitamin K2 exists in the diet, even in the richest food sources. •While the body's friendly bacteria produce some K2, little or none of this K2 is absorbed. Menatetrenone's health benefits extend well beyond the skeletal system. Emerging science is now documenting the role of vitamin K - and specifically of Menatetrenone - in protecting our cardiovascular health, and the health of that all-important organ, the brain. References i. Orimo H, Shiraki M, Tomita A, Morii H, Fujita T, Ohata M. "Effects of menatetrenone on the bone and calcium metabolism in osteoporosis: a double-blind placebo-controlled trial." J Bone Miner Metab 1998; 16(2): 106-12. ii. Iwamoto J, Takeda T, Ichimura S. "Effect of menatetrenone on bone mineral density and incidence of vertebral fractures in postmenopausal women with osteoporosis: a comparison with the effect of etidronate." J Orthop Sci. 2001; 6(6): 487-92. iii. Shiraki M, Shiraki Y, Aoki C, Miura M. "Vitamin K2 (menatetrenone) effectively prevents fractures and sustains lumbar bone mineral density in osteoporosis." J Bone Miner Res. 2000 Mar; 15(3): 515-21. iv. Geleijnse JM, Vermeer C, Jurgers LJ, Grobbee DE, Pols HA, Witteman JC. "Inverse association of dietary vitamin K-2 intake with cardiac eventsand aortic atherosclerosis: the Rotterdam Study." Thromb Haem. 2001 Jul; 85(Suppl): AbsP473. v. Allison AC. "The possible role of vitamin K deficiency in the pathogenesis of Alzheimer's disease and in augmenting brain damage associated with cardiovascular disease." Med Hypotheses. 2001 Aug; 57(2): 151-5. vi. Vermeer C. "Prevention of arterial calcification by vitamin K2." In Miki T (ed). "Vitamin K: A Conference Record. Renewing Bone Metabolism." 2000; Tokyo: Intermedd Inc, 2-21. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. The information and product descriptions appearing on this website are for information purposes only, and are not intended to provide medical advice to individuals. Consult with your physician if you have any health concerns, and before initiating any new diet, exercise, supplement, or other lifestyle changes. ~Vitamin Wagon carries quality products at competitive prices~

Strontium Support II - Advanced Orthomolecular Research

Available at Vitamin Wagon

Strontium Support II Advanced Orthomolecular Research
100% Vegetarian

Strontium Support II is an organic, stable strontium form (not to be confused with the radioactive strontium-90 isotope). Strontium is a trace mineral in the diet whose metabolism is closely tied to that of calcium, and which concentrates in the skeletal system, where it supports the function of osteoblasts (the cells which form new bone) while reducing the differentiation and activity of osteoclasts (the cells which resorb old bone). Extensive evidence supports a role for strontium in supporting skeletal health. 

Strontium:The First Bone-Building Supplement!

Bone loss accelerates suddenly in menopausal women because the drop in estrogen levels causes an increase in the resorption (teardown) of existing bone. But resorption is only half of the story. Age-related bone loss is also caused by a decrease in the formation of new bone tissue.

Existing drugs for treating osteoporosis, as well as calcium and vitamin D supplements, work by reducing bone resorption. But they do not support the formation of new bone. These drugs and nutrients increase the mineralization of bone, but they do not help the body to build new bone tissue. And in fact, within weeks of starting use of antiresorptive drugs like Fosamax,® the body's formation of new bone actually decreases. The resulting bone is less prone to fracture, but is not the same as youthful, healthy bone.

Strontium is a mineral found along with calcium in most foods. Research has long suggested that it may be an essential nutrient required for the normal development, structure, function, and health of the skeletal system. Clinical trials going back into the 1940s have supported this conclusion, but recent studies have provided evidence that it can offer unique nutritional support against loss of bone structure and function.

Strontium Support II conveniently provides high-quality strontium at an effective dose in only two capsules. 

SUPPLEMENT FACTS:

Serving Size: 1 Capsule                                   %   DRI

Strontium (from citrate) ..................341 mg           *

Produced through pharmaceutical synthesis

*Daily value not established..

Other ingredients: none.

Capsule: vegetarian (hydromellose. water).

AOR guarantees that no ingredients not listed on the label have been added to the product. Contains no wheat, gluten, corn, nuts, dairy, soy, eggs, fish or shellfish.

Suggested Use
Take one to two capsules daily on an empty stomach, at least two hours before or after food, calcium or milk, but ensure that daily calcium intake is adequate.  Calcium, food and milk products significantly reduce strontium absorption if taken at the same time.

Main Applications As reported by literature: 
Supports skeletal health.
Source Pharmaceutical synthesis
Pregnancy / Nursing  No studies have been conducted. Best to avoid.

Cautions 
Ensure calcium intake is also adequate. Do not take at the same time as calcium supplements. 

Additional Information:

Animal studies have shown that Strontium supplements both decrease bone resorption, and increase the formation of new bone tissue.
• In animal models, Strontium (in various forms, such as chloride, carbonate, gluconate, and lactate) causes "baby" osteoblasts (bone-building cells) to multiply more quickly.
• Bone tissue cultures which are exposed to Strontium synthesize more bone matrix and new bone collagen. The same amount of calcium has no effect on these parameters.
• In bone tissue culture, Strontium reduces bone resorption at concentrations at which calcium has no effect, prevents the resorption caused by excessive parathyroid hormone, and slows the rate at which immature osteoclasts develop.
• Strontium-supplemented diets boost bone strength in experimental animals without a negative impact on bone quality, even at extremely high doses.

Human clinical trials also support Strontium's ability to both support new bone formation and prevent excessive resorption. 

• • The results of early clinical trials using Strontium (lactate) led researchers to speculate that Strontium increased osteoblast activity. 
• • Bone biopsies from a small human pilot trial revealed an astounding 172.4% increase in new bone formation activity after six months of Strontium (gluconate) supplementation. 
• • The bone-building activity of osteoblasts can be measured using bone-specific alkaline phosphatase, while cross-linked N-telopeptide (NTx) and C-telopeptide (CTx) mark the degradation of bone collagen by ravaging osteoclasts.

 
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